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LOVASTATIN® (Mevacor)

LOVASTATIN® USES: Lovastatin is used, along with a cholesterol-lowering diet, to help lower cholesterol and fats (triglycerides) in the blood. Reducing cholesterol and triglycerides helps prevent strokes and heart attacks.

HOW TO USE LOVASTATIN®: Take this medication by mouth usually once or twice daily with or without food; or as directed by your doctor. The dosage is based on your medical condition and response to therapy.

It may take up to 2 weeks before the full benefit of this drug takes effect. It is important to continue taking this medication even if you feel well. Most people with high cholesterol or triglycerides do not feel sick.

LOVASTATIN® SIDE EFFECTS: Headache, nausea, diarrhea, constipation, gas, or stomach upset/pain may occur. If any of these effects persist or worsen, notify your doctor promptly.

Tell your doctor immediately if any of these unlikely but serious side effects occur: joint pain, muscle pain or weakness, fever, unusual tiredness, chest pain, swelling in the arms or legs, dizziness.

Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: changes in taste, yellowing eyes and skin, dark urine, change in the amount of urine, vision problems, black stool, severe stomach pain.

An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing.

If you notice other effects not listed above, contact your doctor or pharmacist.

LOVASTATIN® PRECAUTIONS: This medication is not recommended for use if you have the following medical conditions: liver problems.

Tell your doctor your medical history, especially of: heart disease, kidney problems, eyeproblems (e.g., cataracts), thyroid problems, uncontrolled seizures, recent serious infection, recent major surgery, low blood pressure, alcohol use, any allergies (especially to other "statin" drugs).

Daily use of alcohol may increase your chance for serious side effects. Limit alcoholic beverages. This medication must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. It is recommended that women of child-bearing age use effective birth control measures while taking this drug since lovastatin may cause fetal harm.

Based on information of related drugs, this medication may pass into breast milk and have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially: clofibrate, gemfibrozil, cyclosporine, macrolide antibiotics (e.g., clarithromycin, erythromycin), azole antifungals (e.g., itraconazole, ketoconazole), niacin (nicotinic acid), protease inhibitors (e.g., indinavir, ritonavir), nefazodone, verapamil, "blood thinners" (e.g., warfarin).

Do not eat grapefruit or drink grapefruit juice while using this medication unless your doctor instructs you otherwise.

Do not start or stop any medicine without doctor or pharmacist approval.

LOVASTATIN® OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: severe vomiting.

LOVASTATIN® NOTES: Do not share this medication with others. Laboratory and/or medical tests (e.g., liver function tests) may be performed to monitor your progress. For best results, this medication should be used along with exercise and a low-cholesterol/low-fat diet. Consult your doctor.

LOVASTATIN® MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 56 and 86 degrees F (13 to 30 degrees C).

IMPORTANT NOTE: This information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. No liability can be taken as a result of using this information.

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